sybyl x 2 0 (Tripos Inc)

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Tripos Inc sybyl x 2 0
Sybyl X 2 0, supplied by Tripos Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sybyl/0+2+sybyl+x/pm42105143-395-11-13
Average 86 stars, based on 1 article reviews

sybyl x 2 0 - by Bioz Stars, 2026-09

86/100 stars

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other:

Article Title: Synthesis, cytotoxicity and HQSAR study of amides-fused isosteviol derivatives as potential anti-colorectal cancer agents.
Article Snippet: A series of novel amide-fused isosteviol derivatives were designed and synthesized.. Their cytotoxicities in vitro against HCT-116 cells were screened.. The preliminary bioassays indicated that most of the title compounds exhibited noteworthy cytotoxicity.

Software:

Article Title: Integrin antagonists
Article Snippet: .. Software systems (e.g., computer programs) used to generate representations or perform the fitting analyses include, for example: MCSS, Ludi, QUANTA, Insight II, Cerius2, CHarMM, and Modeler from Accelrys, Inc. (San Diego, CA); SYBYL, Unity, FleXX, and LEAPFROG from TRIPOS, Inc. (St. Louis, MO); AUTODOCK (Scripps Research Institute, La Jolla, CA); GRID (Oxford University, Oxford, UK); DOCK (University of California, San Francisco, CA); and Flo+ and Flo99 (Thistlesoft, Morris Township, NJ). .. Other useful programs include ROCS, ZAP, FRED, Vida, and Szybki from Openeye Scientific Software (Santa Fe, NM); Maestro, Macromodel, and Glide from Schrodinger, LLC (Portland, OR); MOE (Chemical Computing Group, Montreal, Quebec), Allegrow (Boston De Novo, Boston, MA), and GOLD (Jones et al., J. Mol.

Residue:

Article Title: A glyco-engineering approach for site-specific conjugation to Fab glycans
Article Snippet: .. Structural manipulation was done in Sybyl (Tripos, Inc.), including site residue mutagenesis, N -GlcNAc linkage and conformational analysis. ..

Mutagenesis:

Binding Assay:

Article Title: Ligand and structure based hierarchical virtual screening cascade for finding novel epidermal growth factor receptor inhibitors.
Article Snippet: Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase, is located upstream of a complex signal transduction cascade that regulates cell proliferation, survival, adhesion, migration, and differentiation (Yarden, 2001).. The aberrant activity of this receptor family members has been shown to play a key role in the development and growth of tumor cells (Passaro et al., 2021).. The EGFR family contains four members: EGFR/ErbB-1, HER2/ ErbB-2, HER3/ErbB-3, and HER4/ErbB-4; and EGFR is one major component to form dimer acting as both receptor and kinase, therefore, activating the signaling pathway (Holbro et al., 2003; Normanno et al., 2006).

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